Blys antagonists and uses thereof

Details Blys antagonists and uses thereof Blys antagonists and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01)

Patent

CA 2526402

The present invention relates to polypeptides that block BlyS signaling nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of BlyS signaling .

La présente invention concerne des polypeptides qui bloquent la signalisation de BLyS, des molécules d'acides nucléiques codant pour ces polypeptides, ainsi que des compositions comprenant lesdits polypeptides. L'invention concerne en outre des méthodes permettant de traiter une maladie immunologique ou un cancer au moyen des polypeptides et des compositions selon l'invention. L'invention concerne par ailleurs des méthodes d'identification d'inhibiteurs de la signalisation de BLyS.

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