Bmp-12, bmp-13 and tendon-inducing compositions thereof

Details Bmp-12, bmp-13 and tendon-inducing compositions thereof Bmp-12, bmp-13 and tendon-inducing compositions thereof

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/18 (2006.01) A61L 27/22 (2006.01) A61L 27/36 (2006.01) C07K 14/51 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2176942

Bone morphogenetic proteins BMP-12 and BMP-13 have been cloned. Compositions of these proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.

Les protéines morphogénétiques osseuses BMP-12 et BMP-13 ont été clonées. Des compositions de ces protéines favorisant l'induction de tissus de type tendon/ligament sont décrites. Lesdites compositions sont utiles dans le traitement des tendinites et des imperfections de tendons et ligaments, ainsi que pour la réparation de tissus apparentés.

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