Body weight gain inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/421 (2006.01) A61K 31/195 (2006.01) A61K 31/235 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 263/32 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2390932

Body weight gain inhibitors comprises PPAR.gamma. agonist-like substances, which contain PPAR.delta. agonist-like substances such as compounds represented by general formula (I) wherein R1 represents optionally substituted hydrocarbyl, etc.; X represents a bond, etc.; Y represents oxygen, etc.; the ring A represents a heterocycle, etc.; R2 represents hydrogen, etc.; R3 represents-OR9, etc.; and R4 and R5 represent each hydrogen, etc., are useful in treating diabetes, etc.

L'invention concerne des inhibiteurs de prise de poids comprenant des substances de type agoniste PPAR.gamma. contenant des substances de type PPAR.delta., notamment des composés de formule générale (I), dans laquelle R1 représente éventuellement un hydrocarbonyle substitué, etc.; X représente une liaison, etc.; Y représente un oxygène, etc.; le cycle A représente un hétérocycle, etc.; R2 représente un hydrogène, etc.; R3 représente-OR9, etc.; et R4 et R5 représentent chacun un hydrogène, etc. Ces composés sont utiles dans le traitement du diabète entre autres.

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