C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61P 35/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2405704
The present invention encompasses novel peptides that are antagonists to bombesin and bombesin like peptides and are useful in the treatment of cancer. The invention particularly relates to the design and synthesis of the novel peptides incorporating .alpha.,.alpha.-amino acids in a site specific manner. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.
La présente invention concerne de nouveaux peptides, en l'occurrence des antagonistes de la bombésine et des peptides du type bombésine, qui sont utiles dans le traitement du cancer. L'invention concerne, en particulier, la conception et la synthèse de ces nouveaux peptides qui comprennent des .alpha.,.alpha.-acides aminés d'une manière spécifique au site. L'invention concerne, en outre, des procédés de génération desdits peptides, des compositions les renfermant et les applications pharmacologiques de ces peptides, notamment dans le traitement et la prévention du cancer.
Burman Anand C.
Jaggi Manu
Mathur Archna
Mukherjee Rama
Prasad Sudhanand
Dabur Pharma Ltd.
Dabur Research Foundation
Marks & Clerk
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