Bone graft composites and spacers

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/54 (2006.01) A61L 27/24 (2006.01) A61L 27/36 (2006.01)

Patent

CA 2293354

A bone graft substitute including a composition of natural selectively deactivated bone material which has been processed to remove associated non- collagenous bone proteins, said bone material containing native collagen materials and naturally associated bone minerals and substantially free from native non-collagenous protein, and a therapeutically effective amount to stimulate bone growth of a bone growth factor in synergistic combination with said bone material. Spacers composed of the bone graft substitute composition and methods for using the spacers are also provided.

Cette invention se rapporte à un substitut de greffe osseuse qui contient une composition de matière osseuse naturelle sélectivement désactivée, que l'on a traitée pour en éliminer les protéines osseuses non collagènes associées, cette matière osseuse contenant des matières au collagène natives et des minéraux osseux naturellement associés et étant sensiblement exempte de protéine non collagène native, ainsi qu'une quantité, thérapeutiquement efficace pour stimuler la croissance osseuse, d'un facteur de croissance osseuse en combinaison synergique avec cette matière osseuse. Des écarteurs constitués par cette composition de substitut de greffe osseuse ainsi que des procédés d'utilisation de ces écarteurs sont également présentés.

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