Bone growth factor

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/51 (2006.01) A61K 38/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2508765

A compound having bone stimulatory activity. In Formula (I), X1 and X10 are positively charged polar amino acids; X4 and X8 are negatively charged polar amino acids; X5 is an aromatic amino acid; X2, X3, X6 and X7 are non polar neutral amino acids or uncharged polar amino acids; Z represents a blocking group; and n is an integer from 1 to 3.

L'invention concerne un composé présentant une activité de stimulation osseuse. Dans la formule (I), X¿1? et X¿10? représentent des acides aminés polaires chargés positivement ; X¿4? et X¿8? représentent des acides aminés polaires chargés négativement ; X¿5? représente un acide aminé aromatique ; X¿2?, X¿3?, X¿6? et X¿7? représentent des acides aminés neutres non polaires ou des acides aminés polaires non chargés ; Z représente un groupe de blocage ; et n représente un entier compris entre 1 et 3.

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