A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 31/70 (2006.01) A61K 35/34 (2006.01) A61K 47/42 (2006.01) A61K 48/00 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2235025
A cardiogenic composition comprising a purified mixture of a transforming growth factor-.beta. protein and a fibroblast growth factor is disclosed. In another embodiment, the present invention is a method of inducing cardiogenesis in cells of a non-cardiac lineage comprising the steps of exposing cells to the composition and observing the development of cardiac cells.
L'invention a trait à une composition cardiogène comportant un mélange purifié d'une protéine du facteur de croissance transformant beta et d'un facteur de croissance des fibroblastes. Dans un autre mode de réalisation, cette invention porte sur une méthode permettant d'induire une cardiogenèse dans des cellules d'une lignée non cardiaque, laquelle méthode consiste à mettre en contact des cellules avec ladite composition et à observer le développement de cellules cardiaques.
Baker John E.
Barron Matthew R.
Brogley Michele A.
Lough John W. Jr.
Zhu Xiaolei
Fetherstonhaugh & Co.
Mcw Research Foundation Inc.
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