Bone precursor compositions

A - Human Necessities – 61 – L

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Details

A61L 24/02 (2006.01) A61L 27/12 (2006.01) A61L 27/38 (2006.01) A61L 27/46 (2006.01)

Patent

CA 2353949

Bone precursor compositions, methods of preparation and use are described. Bone precursor compositions include a calcium cement which is suitable for injection, wherein the calcium cement includes monobasic calcium phosphate monohydrate and beta-tricalcium phosphate. The bone precursor compositions can further include biopolymer foams, collagen, extracellular matrix components, therapeutic agents, or biopolymer fibers. The bone precursor compositions can also include or be conditioned with cells, such as connective tissue cells, preferably bone tissue cells.

La présente invention concerne des compositions précurseurs osseuses ainsi que leurs procédés de préparation et leurs utilisations. Ces compositions comprennent un ciment au calcium injectable fait d'un monohydrate phosphate de calcium monobasique et un phosphate béta-tricalcique. Ces compositions précurseurs osseuses peuvent également renfermer des mousses biopolymères, du collagène, des composantes de matrice extracellulaires, des agents thérapeutiques ou des fibres biopolymères. Elles peuvent aussi renfermer des cellules du tissu conjonctif, de préférence des cellules de tissu osseux, ou être conditionnées avec lesdites cellules.

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