Bone-related cadherin-like protein and process for its...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/51 (2006.01) C07K 14/705 (2006.01) C07K 16/22 (2006.01) C12N 15/62 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2104997

Abstract of the Disclosure A bone-related protein named OSF-4 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein of the cadherin family. OSF-4 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-4 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.

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