Bone-related carboxypeptidase-like protein and process for...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/57 (2006.01) A61K 38/48 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C12N 9/48 (2006.01) C12N 9/64 (2006.01) C12N 15/62 (2006.01) C12P 21/08 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2104998

Abstract of the Disclosure A bone-related carboxypeptidase-like protein named OSF-5 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein which belongs to a group of carboxypeptidase molecules. OSF-5 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-5 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.

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