Bone-seeking complexes of technetium-99m

Details Bone-seeking complexes of technetium-99m Bone-seeking complexes of technetium-99m

C - Chemistry, Metallurgy

07

F

167/48

C07F 9/38 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1213519

ABSTRACT Bone-Seeking Complexes of Technetium-99m A composition for use in the preparation of a Technetium-99m bone-scanning agent comprises a mixture of ethylene glycol-1,2-bisphosphonic acid or a non-toxic salt thereof together with a reducing agent for pertechnetate. Technetium-99m, as an aqueous solution of pertechnetate, is added to the composition to form a complex of Technetium-99m and the bisphosphonate. The complex is useful as a bone- scanning agent and is rapidly taken up in bone to give scans of high definition.

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