Bone tissue substitute, a solidifiable bone precursor and...

Details Bone tissue substitute, a solidifiable bone precursor and... Bone tissue substitute, a solidifiable bone precursor and...

A - Human Necessities

61

L

A61L 27/46 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2684166

The present concerns a solidifiable bone precursor composition which can be used to produce a mineralized substitute bone tissue material and the method of making the substitute bone tissue material.. The substitute bone tissue material includes a collagen matrix comprising pores, and an apatitic mineral within the pores of general formula: A s(TO x)t(QO x)u Z y wherein A is a cation selected from Na, K, Mg, Ca, Fe3+, Al3+ or combinations thereof, T and Q are an anion oxide selected from P or C, Z is a H, OH or a halogen group, and s is 1 to 10, x is 2 to 4, t is 1 to 3, is 0 to 3 and y is 0 to 3 . The solidifiable bone precursor composition includes: an aqueous dispersion comprising: at least one cation; and a polyphosphate combined to produce a cation-polyphosphate granule; and a collagen.

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