Borate-polyol mixtures as a buffering system

Details Borate-polyol mixtures as a buffering system Borate-polyol mixtures as a buffering system

A - Human Necessities

61

L

A61L 12/14 (2006.01)

Patent

CA 2604813

A buffering system having a pKa which may be selected based on the environment in which the solution is designed to be used. Solutions containing the buffering system according to the present invention include borate-polyol complexes as the primary buffering agents, and may include one or more of the following: an aqueous liquid medium; an antimicrobial component; a surfactant component; a viscosity-inducing component; and/or a tonicity component. The borate-polyol buffering system may be formulated to have a lower pKa than traditional systems.

L'invention concerne un système de tampon dont la valeur pKa peut être sélectionnée selon l'environnement dans lequel la solution est destinée à être utilisée. Les solutions contenant le système tampon de l'invention comprennent des complexes de borate-polyol comme agents tampons primaires, et un ou plusieurs des éléments suivants: milieu liquide aqueux; composant antimicrobien; composant tensioactif; composant augmentant la viscosité; et/ou composant agissant sur la tonicité. Le système de tampon à base de borate-polyol est formulé en vue de présenter une valeur pKa inférieure à celle de systèmes classiques.

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