Bordetella strain expressing the fha hybrid, liposomes and...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 1/21 (2006.01) A61K 39/10 (2006.01) A61K 47/48 (2006.01) C07K 14/235 (2006.01) C12N 1/36 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2267851

The invention concerns a Bordetella strain deficient in the production of toxin and expressing a hybrid protein comprising at least part of the filamentous hemagglutin (FHA) and at least part of a protein heterologous to FHA. The gene coding for the toxin has been eliminated, or at least partially deleted or mutated so as to produce an inactive toxin. This strain can be used as vaccine. The invention also concerns liposomes containing at least part of the FHA protein and at least one protein heterologous to the FHA protein, and the use of FHA for the stimulation of immune responses.

Souche de Bordetella déficiente dans la production de toxine et exprimant une protéine hybride comprenant au moins une partie de l'hémagglutine filamenteuse (FHA) et au moins une partie d'une protéine hétérologue vis-à-vis de la FHA. Le gène codant pour la toxine a été éliminé, ou au moins partiellement délété ou muté afin de produire une toxine inactive. Cette souche peut être utilisée comme vaccin. L'invention est aussi relative à des liposomes contenant au moins une partie de la protéine FHA et au moins une protéine hétérologue à la protéine FHA, ainsi qu'à l'utilisation de la FHA pour la stimulation de réponses immunitaires.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Bordetella strain expressing the fha hybrid, liposomes and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bordetella strain expressing the fha hybrid, liposomes and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bordetella strain expressing the fha hybrid, liposomes and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2064634

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.