Boron-containing small molecules

Details Boron-containing small molecules Boron-containing small molecules

C - Chemistry, Metallurgy

07

H

C07H 23/00 (2006.01) A61K 31/69 (2006.01) A61K 31/7048 (2006.01) A61P 31/00 (2006.01) A61P 31/10 (2006.01) C07F 5/04 (2006.01) C12N 15/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/00 (2006.01) G01N 33/573 (2006.01) C07H 19/04 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2635680

This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.

L'invention concerne des composés utiles pour le traitement d'infections fongiques, plus spécifiquement pour le traitement topique de l'onychomycose et/ou d'infections fongiques cutanées. L'invention concerne des composés qui sont actifs contre les champignons et qui présentent des propriétés qui permettent au composé, lorsque placé en contact avec un patient, d'atteindre la partie spécifique de la peau, de l'ongle, du poil, de la griffe ou du sabot infectés par le champignon. En particulier, les composés de l'invention présentent des propriétés physiochimiques qui facilitent la pénétration de la table unguéale.

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