C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/22 (2006.01) A61K 31/409 (2006.01) A61K 41/00 (2006.01) C07B 59/00 (2006.01) C07F 5/02 (2006.01) C09B 47/04 (2006.01) C09B 47/067 (2006.01)
Patent
CA 2518934
The present invention relates to meta l-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta l-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.
La présente invention concerne des métal-phthalocyanines portant au moins un groupe contenant des isotopes de bore ?11¿B ou ?10¿B, liés par covalence aux positions périphériques du noyau métal-phthalocyanine. L'invention concerne également leurs procédés de préparation, les compositions pharmaceutiques les contenant et leur utilisation dans le traitement de pathologies néoplastiques et dysplastiques.
Chiti Giacomo
Dei Donata
Fabris Clara
Giuntini Francesca
Jori Giulio
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.p.a.
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