Boronated nucleosides

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 5/02 (2006.01) A61K 31/70 (2006.01) C07D 473/00 (2006.01) C07D 473/18 (2006.01) C07D 473/34 (2006.01) C07F 7/18 (2006.01) C07F 9/6561 (2006.01) C07H 19/04 (2006.01) C07H 19/06 (2006.01) C07H 19/10 (2006.01) C07H 19/16 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2071936

2071936 9109048 PCTABS00005 A novel class of pharmaceutically active boronated nucleosides are provided. The nucleosides are boronated at a ring nitrogen of the purine or pyrimidine or analogues thereof. Also provided are phosphate esters of these nucleosides and oligomers thereof. Methods of making and using the boronated nucleosides are also disclosed.

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