Boronic acid adducts of rhenium and radioactive isotopes of...

Details Boronic acid adducts of rhenium and radioactive isotopes of... Boronic acid adducts of rhenium and radioactive isotopes of...

C - Chemistry, Metallurgy

07

F

260/383, 260/428

C07F 13/00 (2006.01)

Patent

CA 1284649

ABSTRACT BORONIC ACID ADDUCTS OF RHENIUM DIOXIME COMPLEXES Boronic acid adducts of radioactive isotopes of rhenium dioxime complexes having the formula ReX(Y)3Z, wherein X is an anion; Y is a vicinal dioxime having the formula Image or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are each independently hydrogen, halogen, alkyl, aryl, amino or a 5 or 6-membered nitrogen or oxygen containing heterocycle, or together R1 and R2 are -(CR8R9)N-wherein n is 3, 4, 5 or 6 and R8 and R9 are each independently hydrogen or alkyl; and Z is a boron derivative of the formula B-R3 wherein R3 is hydroxy, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxy, carboxyalkyl, carboxyalkenyl, hydroxyalkyl, hydroxyalkenyl, alkoxyalkyl, alkoxy- alkenyl, haloalkyl, haloalkenyl, aryl,arylalkyl or (R4R5N)-alkyl and R4 and R5 are each independently hydrogen, alkyl or arylalkyl, or R4 and R5 when taken together with the nitrogen atom to which they are attached form a 5 or 6-membered nitrogen containing heterocycle, are useful for labeling biologically active compounds as agents for radiotherapy.

578324

Affiliated with

Also associated with

Rating

Boronic acid adducts of rhenium and radioactive isotopes of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Boronic acid adducts of rhenium and radioactive isotopes of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Boronic acid adducts of rhenium and radioactive isotopes of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1200072