Boronic acid salts ant their use in the treatment of thrombosis

Details Boronic acid salts ant their use in the treatment of thrombosis Boronic acid salts ant their use in the treatment of thrombosis

A - Human Necessities

61

K

A61K 31/69 (2006.01) C07D 207/08 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2535792

Salts of a peptide boronic acid drug, for example of Cbz-(R)-Phe-(S)-Pro-(R)- Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from an organic nitrogen-containing compound. The salts are use in the treatment of thrombosis.

L'invention concerne des sels d'un médicament d'acide boronique peptidique, par exemple de Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)¿2?. Le contre-ion du boronate peut être un métal alcalin ou peut être dérivé d'un composé contenant de l'azote organique. Ces sels sont utilisés dans le traitement de la thrombose.

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