Boronic acid salts useful in parenteral formulations for...

A - Human Necessities – 61 – K

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A61K 31/69 (2006.01) C07D 207/08 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2536010

Parenteral pharmaceutical formulations comprising base addition salts of a peptide boronic acid drug, for example of Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or alkaline earth metal.

L'invention concerne des compositions pharmaceutiques parentérales constituées de sels d'addition à une base d'un médicament d'acide boronique peptidique, par exemple de Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)¿2?. Le contre-ion du boronate peut être un métal alcalin ou un métal alcalino-terreux.

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