Boropeptide inhibitors of enteropeptidase and their uses in...

Details Boropeptide inhibitors of enteropeptidase and their uses in... Boropeptide inhibitors of enteropeptidase and their uses in...

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) A61K 38/00 (2006.01) A61P 3/04 (2006.01) C07K 5/08 (2006.01)

Patent

CA 2707549

The present invention relates to novel compounds, particularly derivatives of boroarginine, boroornithine and borolysine that selectively modulate, regulate, and/or inhibit enteropeptidase. The invention also relates to compositions, particularly pharmaceutical compositions, as well as methods to treat excess weight, obesity and diseases associated with an abnormal fat metabolism.

Cette invention concerne de nouveaux composés, en particulier des dérivés de la boroarginine, de la boroornithine et de la borolysine qui modulent, régulent et/ou inhibent de manière sélective l'entérokinase. L'invention concerne également des compositions, en particulier des compositions pharmaceutiques, ainsi que des procédés permettant de traiter l'excès de poids, l'obésité et les maladies associées avec un métabolisme anormal des lipides.

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