A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/08 (2006.01)
Patent
CA 2631927
The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.
L'invention concerne des nanoémulsions contenant des toxines botuliniques. Dans un mode de réalisation, les nanoémulsions sont obtenues par microfluidisation haute pression et elles présentent une distribution granulométrique comprise exclusivement entre 10 et 300 nm. Les nanoémulsions selon l'invention sont utiles dans le traitement cosmétique et médical des états de contractures musculaires. Les toxines botuliniques peuvent, par exemple, détendre les muscles faciaux de sorte que les rides cutanées deviennent plus lisses et moins visibles. L'invention concerne également une préparation cosmétique pouvant être autoadministrée à domicile, sans surveillance médicale.
Edelson Jonathan
Nicolosi Robert
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
University Of Massachusetts Lowell
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