A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/265 (2006.01) A61K 39/102 (2006.01) C07K 14/05 (2006.01) C12N 15/869 (2006.01)
Patent
CA 2738664
The disclosure relates generally to the treatment or prevention of disease in cattle. More particularly, the invention is directed to the production and use of modified bovine herpesvirus 1 (BHV-1) and their use in compositions and vaccines that protect cattle from BHV-1 infection while not suppressing the immunological response in the host. In one example, the invention is directed to the use of modified BHV-1, administered with additional immunogens, either through co-administration and/or through administration in combination vaccines, and the use of these vaccines for the protection of cattle from disease. In one example, use of the modified BHV-1 in the administered compositions facilitates an immune response to or against the additional immunogens.
L'invention porte d'une manière générale sur le traitement ou la prévention d'une maladie du bétail. Plus particulièrement, l'invention porte sur la production et l'utilisation d'un virus de l'herpès bovin modifié 1 (BHV-1) et sur son utilisation dans des compositions et des vaccins qui protègent le bétail d'une infection par BHV-1 tout en ne supprimant pas la réponse immunologique chez l'hôte. Selon un exemple, l'invention porte sur l'utilisation de BHV-1 modifié, administré avec des immunogènes supplémentaires, soit par co-administration et/ou par administration dans des vaccins combinés, et sur l'utilisation de ces vaccins pour la protection du bétail vis-à-vis de la maladie. Selon un exemple, l'utilisation du BHV-1 modifié dans les compositions administrées facilite une réponse immunitaire dirigée sur ou contre les immunogènes supplémentaires.
Albee Lee David II
Harland Richard
Kaufer Benedikt B.
Osterrieder Nikolaus
Patel Mayur Navnitbhai
Cornell University
Novartis Ag
Ridout & Maybee Llp
LandOfFree
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