Bovine herpesvirus type 1 deletion mutants, vaccines based...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/00 (2006.01) A61K 39/245 (2006.01) A61K 39/42 (2006.01) C12N 15/38 (2006.01) C12P 21/08 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2110519

Deletion mutant of bovine herpesvirus type 1 which has a deletion in the glycoprotein gE-gene. The mutant may further have a deletion in the thymidine kinase gene and/or the glycoprotein gI-gene; or have an insertion of a heterologous gene. Rec- ombinant nucleic acid which comprises the gE-gene or a part thereof. Glycoprotein gE, peptides based thereon and complexes of the glycoproteins gE and gI, and antibodies against them. Vaccines and diagnostic kits comprising any one of these materials.

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