Bovine polynucleotide vaccine for the intradermal route

Details Bovine polynucleotide vaccine for the intradermal route Bovine polynucleotide vaccine for the intradermal route

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 39/155 (2006.01) A61K 39/265 (2006.01)

Patent

CA 2261334

A bovine polynucleotide vaccine formula including an intradermally effective amount of a plasmid consisting of a combination of a DNA sequence coding for a bovine pathogen immunogen and a promoter enabling in vivo expression of said immunogen in skin cells, is disclosed. Said vaccine formula is suitable for intradermal delivery by means of a liquid jet delivery apparatus. The portable bovine vaccination equipment includes a liquid jet delivery apparatus and a flask suitable for containing a plurality of doses of such a vaccine formula, and the delivery apparatus is designed to deliver a vaccine formula dose intradermally.

La formule de vaccin bovin polynucléotidique comprend une quantité efficace par voie intradermique d'un plasmide associant une séquence d'ADN codant pour un immunogène d'un agent pathogène bovin et un promoteur permettant l'expression de cet immunogène in vivo dans les cellules de la peau, cette formule de vaccin étant adaptée à l'administration intradermique par un appareil d'administration par jet liquide. L'installation portative de vaccination bovine comprenant un appareil d'administration par jet liquide et un flacon adapté comprenant plusieurs doses d'une telle formule de vaccin, l'appareil d'administration étant conçu pour délivrer une dose de formule de vaccin en intradermique.

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