Bradykinin analogs as selective inhibitors of cell activation

Details Bradykinin analogs as selective inhibitors of cell activation Bradykinin analogs as selective inhibitors of cell activation

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/02 (2006.01) A61K 38/04 (2006.01) A61K 38/17 (2006.01) C07K 5/09 (2006.01) C07K 7/18 (2006.01) C07K 14/81 (2006.01)

Patent

CA 2288027

The present invention provides bradykinin peptide analogs, compositions, and methods of inhibiting thrombin-induced platelet and other cell activation. The bradykinin analogs comprise single or multiple peptide segments. The invention also provides a method for identifying compounds that selectively inhibit thrombin-induced platelet and other cell activation.

La présente invention concerne des analogues de la bradykinine, des compositions à base de tels peptides, et des procédés permettant d'inhiber l'activation plaquettaire ou cellulaire induite par la thrombine. Ces analogues de bradykinine sont mono ou multisegments. L'invention concerne également un procédé permettant d'identifier des composés inhibant sélectivement l'activation plaquettaire ou cellulaire induite par la thrombine.

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