Bradykinin b1 receptor antagonists

Details Bradykinin b1 receptor antagonists Bradykinin b1 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/506 (2006.01) A61P 29/00 (2006.01) C07C 255/58 (2006.01) C07D 207/325 (2006.01) C07D 215/42 (2006.01) C07D 215/48 (2006.01) C07D 217/22 (2006.01) C07D 239/42 (2006.01) C07D 239/46 (2006.01) C07D 239/48 (2006.01) C07D 311/68 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 5

Patent

CA 2379064

Bradykinin B1 receptor antagonists of formula (I) are disclosed. The compounds are useful for treating diseases associated with inappropriate bradykinin receptor activity, such as diabetic vasculopathy, inflammation, pain, hyperalgesia, asthma, rhinitis, septic shock, atherosclerosis and multiple sclerosis. Pyrimidines, triazines, and anilines in which Q is imidazolyl or pyrrolyl are particularly preferred.

La présente invention concerne des antagonistes du récepteur B¿1? de la bradykinine représentés par la formule générale (I). Ces composés conviennent au traitement d'affections liées à la dysactivité du récepteur de la bradykinine, telles que vasculopathie diabétique, inflammation, douleur, hyperalgie, asthme, rhinite, choc septique, athérosclérose, et sclérose en plaques. On préfère particulièrement les pyrimidines, triazines, et anilines dans lesquelles Q est imidazolyle ou pyrrolyle.

Affiliated with

Also associated with

Rating

Bradykinin b1 receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bradykinin b1 receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bradykinin b1 receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1771012