Brain glycogen phosphorylase cancer antigen

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 35/14 (2006.01) A61K 38/10 (2006.01) A61K 38/45 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 9/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2258564

The invention describes brain glycogen phosphorylase tumor rejection antigen precursors, including nucleic acids encoding such tumor rejection antigen precursors, tumor rejection antigen peptides or precursors thereof and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a brain glycogen phosphorylase tumor rejection antigen or precursor thereof.

L'invention concerne des précurseurs d'antigènes de rejet de tumeur sous forme de phosphorylase agissant sur le glycogène cérébral, y compris les acides nucléiques codant ces précurseurs, les peptides antigéniques de rejet de tumeur ou leurs précurseurs et les anticorps apparentés. On décrit des procédés et des produits pour le diagnostic et le traitement des états caractérisés par l'expression d'un antigène de rejet de tumeur, sous la forme d'une phosphorylase agissant sur le glycogène cérébral, ou de son précurseur.

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