A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 1/02 (2006.01) A61B 16/00 (2006.01) A61M 16/00 (2006.01) A61M 1/10 (2006.01)
Patent
CA 2163891
The invention discloses a method for preserving organs in brain-dead humans or cadavers which allows additional time for the organs to remain viable such that they may be harvested for subsequent transplantation. The method includes the steps of catheterizing the vessels or tissues around the organ sought to be preserved, introducing a temperature controlled solution to cool the organ to inhibit degenerative metabolism, oxygenating the organ and inhibiting free radical damage. The temperature controlled organ preservation solution includes perfluorocarbons, antioxidants, tissue damage reversing and protecting agents, carrier vehicles, diluents, nutrients, and anticoagulating agents. A device which performs this method is also disclosed. This device includes a fluid reservoir (30), an oxygen tank (34), a heat exchanger (38) and removable catheter lines (60). Also disclosed is a method for brain resuscitation involving injections of "warm" resuscitation solution followed by injection of "cool" and oxygenated resuscitation solution.
Procédé de préservation d'organes sur des humains en état de mort cérébrale ou sur des cadavres, allongeant la durée de viabilité des organes pour permettre leur prélèvement en vue de transplantations. Le procédé consiste à cathétériser les vaisseaux ou tissus entourant l'organe qu'on cherche à préserver, à introduire une solution à température contrôlée pour refroidir l'organe, y inhiber le métabolisme dégénératif, l'oxygéner et empêcher les atteintes aux radicaux libres. Ladite solution comprend des perfluorocarbones, des antioxydants, des agents de réversion des dommages, des agents protecteurs, des excipients, des diluants, des nutriments et des anticoagulants. L'invention porte également sur un dispositif permettant d'accomplir l'opération et comportant un réservoir (30) de fluide, une bouteille d'oxygène (34), un échangeur de chaleur (38), et des tubes de cathéters retirables (60). L'invention porte enfin sur une méthode de revitalisation du cerveau consistant en injections alternées de solutions revitalisantes "chaude", puis "froide" et oxygénante.
Goldman Robert M.
Klatz Ronald M.
Goudreau Gage Dubuc
Life Resuscitation Technologies Inc.
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