Brca1-based breast or ovarian cancer prevention agents and...

Details Brca1-based breast or ovarian cancer prevention agents and... Brca1-based breast or ovarian cancer prevention agents and...

A - Human Necessities

61

K

A61K 31/403 (2006.01) A61K 31/41 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2705812

A pharmaceutical composition for use in treating, inhibiting, and/or preventing breast and/or ovarian cancer can include: a molecule having a structure of one of Compounds 1- 38, pharmaceutically acceptable salt thereof, or analog thereof; and a pharmaceutically acceptable carrier containing the compound. The pharmaceutically acceptable carrier can be configured for oral, systemic, transdermal, intranasal, suppository, parenteral, intramuscular, intravenous, or subcutaneous administration. The compound can be present in the composition in a therapeutically effective amount for treating, inhibiting, and/or preventing breast and/or ovarian cancer. Also, the compound can be present in a therapeutically effective amount for enhancing production of BRCA1.

L'invention concerne une composition pharmaceutique destinée à être utilisée dans le traitement, l'inhibition, et/ou la prévention du cancer du sein et/ou des ovaires pouvant comprendre : une molécule ayant la structure d'un des composés 1 à 38, du sel pharmaceutiquement acceptable de ceux-ci, ou d'analogues à ceux-ci; et un porteur pharmaceutiquement acceptable contenant le composé. Le porteur pharmaceutiquement acceptable peut être configuré pour une administration orale, systémique, transdermique, intranasale, sous forme de suppositoire, parentérale, intramusculaire, intraveineuse, ou sous-cutanée. Le composé peut être présent dans la composition en quantité thérapeutiquement efficace pour traiter, inhiber, et/ou prévenir le cancer du sein et/ou des ovaires. De plus, le composé peut être présent selon une quantité thérapeutiquement efficace pour améliorer la production de BRCA1.

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