A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/19 (2006.01) A61K 31/198 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2712080
The present invention comprises methods and composi-tions for producing and/or enhancing an immunological response in a sub-ject against a target moiety such as a disease-related moiety by administra-tion of an antigenic version of the target moiety having one or more unnat-ural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which anti-body is cross reactive with the natural target moiety.
Cette invention comprend des procédés et des compositions permettant de produire et/ou de stimuler une réponse immunologique chez un sujet dirigée contre une fraction cible (par exemple une fraction associée à une maladie) par administration dune version antigénique de la fraction cible comportant un ou plusieurs acide(s) aminé(s) non naturel(s) et/ou par administration dun anticorps dirigé contre une version dune fraction cible ayant un ou plusieurs acide(s) aminé(s) non naturel(s), ledit anticorps manifestant une réaction croisée avec la fraction cible naturelle.
Grunewald Jan
Lerner Richard A.
Perera Roshan
Schultz Peter G.
Smider Vaughn V.
Fetherstonhaugh & Co.
The Scripps Research Institute
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