C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 7/04 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2445532
The present invention relates to seven isolated breast cancer-associated (BCA) polynucleotides, polypeptides, and variants thereof. The invention also relates to BCA antagonists. The invention also encompasses pharmaceutical compositions comprising BCA polynucleotides, BCA polypeptides, or BCA antagonists. The invention also contemplates methods for preventing or treating cancer, particularly breast cancer, comprising administering to a patient in need of such treatment a composition comprising a BCA polynucleotide, polypeptide, antagonist, or variant thereof. The invention also relates to methods for diagnosing, staging or determining a prognosis of a BCA-related disorder.
L'invention concerne sept polynucléotides isolés, associés au cancer du sein, y compris des polypeptides et les variants correspondants. L'invention concerne également des antagonistes associés au cancer du sein, ainsi que des compositions pharmaceutiques renfermants des polynucléotides, des polypeptides, ou des antagonistes associés au cancer du sein. L'invention concerne par ailleurs des procédés relatifs à la prévention ou au traitement du cancer, en particulier le cancer du sein, qui consistent à administrer aux personnes traitées une composition renfermant un polynucléotide, un polypeptide ou un antagoniste associé au cancer du sein, ou bien un variant correspondant. L'invention concerne enfin des procédés relatifs au diagnostic, à la détermination des stades ou à l'établissement d'un pronostic pour un trouble lié au cancer du sein.
Osler Hoskin & Harcourt Llp
Sunnybrook & Women's College Health Sciences Centre
LandOfFree
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