C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4196 (2006.01) A61P 35/00 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 471/18 (2006.01)
Patent
CA 2730251
Bridged bicyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase AxI. Methods of using the compounds in treating diseases or conditions associated with AxI activity are also disclosed.
L'invention porte sur des triazoles substitués par hétéroaryle bicycliques pontés et sur des compositions pharmaceutiques contenant les composés, qui sont utiles pour inhiber l'activité du récepteur à activité tyrosine kinase Axl. L'invention porte également sur des procédés d'utilisation des composés dans le traitement de maladies ou affections associées à une activité d'Axl.
Goff Dane
Heckrodt Thilo J.
Holland Sacha
Litvak Joane
Singh Rajinder
Gowling Lafleur Henderson Llp
Rigel Pharmaceuticals Inc.
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