Bridged cyclic ketal derivatives

Details Bridged cyclic ketal derivatives Bridged cyclic ketal derivatives

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A61K 31/34 (2006.01) A61K 31/70 (2006.01) C07D 493/08 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2100257

2100257 9212159 PCTABS00014 Compounds are described of formula (I). These compounds inhibit the enzyme squalene synthase and/or are intermediates for the preparation of compounds which inhibit the enzyme squalene synthase. Compounds of the invention may be formulated for use in a variety of conditions where a lowering of the level of blood plasma cholesterol in animals would be beneficial and for use in combating fungal infections in animals.

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