Bridged heterocycles as hiv integrase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 498/18 (2006.01) A61K 31/529 (2006.01) A61K 31/5386 (2006.01) A61K 31/55 (2006.01) A61P 31/18 (2006.01) C07D 471/08 (2006.01) C07D 471/18 (2006.01) C07D 487/08 (2006.01) C07D 493/18 (2006.01)

Patent

CA 2718950

The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV. Formule (I).

L'invention concerne de nouveaux composés de la formule I, y compris leurs sels, qui inhibent l'intégrase du VIH et empêchent une intégration virale dans l'ADN humain. Cette action rend les composés utiles pour traiter une infection du VIH et le SIDA. L'invention englobe également des compositions et procédés pharmaceutiques pour traiter les personnes infectées par le VIH.

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