Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors

Details Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/08 (2006.01) A61K 31/46 (2006.01) C07D 451/02 (2006.01) C07D 451/14 (2006.01)

Patent

CA 2525124

In an embodiment, this invention discloses novel gamma secretase inhibitors of Formula (I) wherein the various moieties are described herein. Also disclosed is a method of treating Alzheimer's disease using a compound of Formula I or a composition comprising the compound of Formula (I).

Dans un mode de réalisation, cette invention concerne de nouveaux inhibiteurs de la gamma-sécrétase représentés par la formule (I), dans laquelle les diverses fractions sont décrites dans les pièces descriptives de la demande. Cette invention concerne également un procédé pour traiter la maladie d'Alzheimer en utilisant un composé de la formule (I) ou une composition comprenant ce composé de formule (I).

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