Bridged ring nk1 antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/18 (2006.01) A61K 31/4375 (2006.01) A61K 31/48 (2006.01) A61P 25/22 (2006.01) C07D 471/22 (2006.01) C07D 498/18 (2006.01) C07D 498/22 (2006.01)

Patent

CA 2591079

A compound having the general structure shown in Formula (I): or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.

La présente invention concerne un composé ayant la structure générale présentée dans la formule (I): [La formule chimique doit être insérée ici, car elle apparaît dans l~abrégé sous forme papier] ou des sels et/ou solvates pharmaceutiquement acceptables de celui-ci, qui sont utiles pour traiter des maladies ou pathologies induites par les récepteurs NK1, par exemple divers troubles physiologiques, symptômes ou maladies, y compris le vomissement, la dépression, l~anxiété et la toux.

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