Bridged ring structures as pharmaceutical agents

Details Bridged ring structures as pharmaceutical agents Bridged ring structures as pharmaceutical agents

C - Chemistry, Metallurgy

07

C

C07C 43/23 (2006.01) A61K 31/085 (2006.01)

Patent

CA 2542650

The present invention is directed to 1.alpha.,25-dihydroxyvitamin D3 mimics which modulate the vitamin D receptor (VDR). The invention is further directed to pharmaceutical compositions and methods for the treatment, prevention or amelioration of one or more symptoms of disease or disorder related to the activity of the vitamin D receptor using an effective amount of a compound of formula (I).

La présente invention concerne des analogues de 1.alpha.,25-dihydroxyvitamine D3 modulant le récepteur de la vitamine D (VDR). L'invention concerne en outre des compositions pharmaceutiques et des méthodes destinées à traiter, prévenir ou atténuer un ou plusieurs symptômes d'une maladie ou d'un trouble associé à l'activité du récepteur de la vitamine D au moyen d'une dose efficace d'un composé de formule (I).

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