Bridgehead labelled compounds and methods of using the same

C - Chemistry – Metallurgy – 07 – D

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C07D 213/75 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01)

Patent

CA 2593323

The present invention relates to compounds having the general formula: Y-L-BFR- X wherein BFR is a bridged fused ring system; Y is a targeting group; L is optionally present and is a linker for coupling Y to BFR; and X is halogen (e.g., radiohalogen) or a functional group for labelling.

Cette invention concerne des composés représentés par la formule générale: Y-L-BFR-X, dans cette formule, BFR représente un système annulaire ponté et fondu; Y représente un groupe de ciblage; L est, éventuellement, présent et il est un agent de liaison permettant de relier Y à BFR; et X représente halogène (par exemple, radiohalogène) ou un groupe fonctionnel destiné au marquage.

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