Brittle-coating, soft core dosage form

Details Brittle-coating, soft core dosage form Brittle-coating, soft core dosage form

A - Human Necessities

61

K

A61K 9/28 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/167 (2006.01) A61K 31/192 (2006.01) A61K 31/4402 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2391439

The present invention provides an oral dosage form for delivering active agents having a soft core with an active agent particles, which have an average size of greater than about 50 µm, and a brittle shell encasing the soft core, wherein the weight ratio of drug particles to shell being from about 1:0:0.5 to about 1.0:15.

La présente invention concerne une forme pharmaceutique orale pour l'administration d'agents actifs ayant un noyau mou contenant les particules d'agents actifs, qui a une taille moyenne supérieure à environ 50 nm et une enveloppe friable enrobant le noyau mou, dans laquelle le rapport de poids entre les particules médicamenteuses et l'enveloppe est d'environ 1:0:0,5 à environ 1,0:15.

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