Buccal polar spray or capsule

Details Buccal polar spray or capsule Buccal polar spray or capsule

A - Human Necessities

61

K

A61K 9/48 (2006.01) A61K 9/00 (2006.01) A61K 9/12 (2006.01) A61K 31/40 (2006.01) A61K 31/465 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2252038

A buccal aerosol spray or capsule using a polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises: polar solvent 75-99,8 % compound 0.0025-40 %, flavoring agent 0.05-5 %. The soft bite gelatin capsule of the invention comprises as comprising as fill composition: polar solvent 50-99,8 %, emulsifier 0-20 %, active compound 0.0003-26 %, and flavoring agent 0.05-60 %.

L'invention concerne un pulvérisateur ou une capsule d'aérosols buccaux utilisant un solvant polaire. Ce pulvérisateur ou cette capsule fournissent des composés biologiquement actifs en vue de leur absorption rapide par les muqueuses buccales, ce qui permet d'obtenir un effet très rapidement. Le pulvérisateur d'aérosol buccal selon l'invention comprend 5-50 % de solvant polaire, 0,0025-40 % d'un composé actif, 0,05-5 % d'un agent aromatisant. La capsule de gélatine molle selon l'invention comprend comme composition de remplissage: 75-99 % d'un solvant polaire, 0-20 % d'émulsifiant, 0,0003-35 % de composé actif, et 0,05-60 % d'un agent aromatisant.

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