Buffered coated polystyrene in pregnancy test

G - Physics – 01 – N

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G01N 31/02 (2006.01) G01N 33/76 (2006.01)

Patent

CA 1083957

ABSTRACT OF THE DISCLOSURE The present invention relates to an improved direct agglutination reagent for pregnancy testing which comprises the use of a liquid reagent having the characteristics of agglutination when placed in contact with fluids which contain human chorionic gonadotropin and which comprises a polystyrene latex carrier having a particle size between about 0.15 to about 0.9 microns, said carrier being coated with rabbit anti- human chorionic gonadotropin serum and the reagent being buffered to a pH of about 6.4 with about 0.5M piperazine dihydrochloride-sodium buffer containing 0.0025 to 1M glycine and glycylglycine, 6% sodium chloride and 1 part merthiolate per 5,000 parts of buffer mixture.

267319

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