Buspirone process

Details Buspirone process Buspirone process

C - Chemistry, Metallurgy

07

D

260/263

C07D 401/14 (2006.01) C07D 221/20 (2006.01) C07D 239/30 (2006.01) C07D 239/36 (2006.01)

Patent

CA 1172255

BUSPIRONE PROCESS Abstract of the Invention A new process for the preparation of buspirone is described wherein the 2-pyrimidinyl component thereof is introduced in a final alkylation step involving 2-halopyrimidines. Radioactive labeled buspirone can be conveniently and economically obtained according to the process by employing labeled 2-halopyrimidines such as 2-chloro- pyrimidine-14C and 2-chloropyrimidine-15N2.

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