Butanoic acid derivatives, processes for the preparation...

Details Butanoic acid derivatives, processes for the preparation... Butanoic acid derivatives, processes for the preparation...

C - Chemistry, Metallurgy

07

D

C07D 277/24 (2006.01) C07C 59/13 (2006.01) C07C 59/205 (2006.01) C07C 69/712 (2006.01) C07C 251/58 (2006.01) C07D 213/30 (2006.01) C07D 261/08 (2006.01) C07D 263/56 (2006.01) C07D 307/42 (2006.01) C07D 307/46 (2006.01) C07D 311/30 (2006.01) C07D 333/16 (2006.01) C07D 333/22 (2006.01) C07D 333/28 (2006.01) C07D 333/56 (2006.01)

Patent

CA 2565184

Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and . processes for the preparation of these compounds. Compounds of formula (I) are activators of PPAR.alpha. and PPAR.alpha. isoforms.

La présente invention se rapporte : à des composés représentés par la formule (I), dans laquelle R, R?1¿ et R?2¿ sont tels que définis dans le descriptif de l'invention ; à l'utilisation desdits composés pour traiter la dyslipidémie, l'athérosclérose et le diabète ; à des compositions pharmaceutiques contenant lesdits composés ; et à des procédés de préparation desdits composés. Les composés représentés par la formule (I) sont des activateurs des PPAR-.alpha. et des isoformes des PPAR-.alpha..

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