Butanol derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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167/274, 260/602

C07C 215/08 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01)

Patent

CA 1241345

ABSTRACT 4-mono- and di-isobutylamino butanols of the formula (I): Image (I) or a pharmaceutically acceptable salt thereof wherein R1 and R2 are the same or different and each is selected from the group consisting of hydrogen, halo, hydroxyl, alkyl of 1 to 4 carbon atoms and alkoxy of 1 to 4 carbon atoms and R is hydrogen or isobutyl, are useful for the treatment of circulatory disorders, particularly arrhythmias, in humans and animals.

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