Bvdv virus-like particles

Details Bvdv virus-like particles Bvdv virus-like particles

C - Chemistry, Metallurgy

12

N

C12N 15/40 (2006.01) A61K 39/12 (2006.01) C07K 14/18 (2006.01) C12N 7/04 (2006.01) C12N 15/869 (2006.01)

Patent

CA 2414339

The present invention relates to bovine viral diarrhea virus (BVDV) virus-like particles, a polycistronic RNA and DNA corresponding thereto encoding a polyprotein of BVDV structural proteins that are sufficient to form BVDV virus- like particles, a viral vector encoding factors and structural proteins for the assembly of BVDV virus-like particles, a vaccine comprising BVDV virus- like particles, a diagnostic kit and methods for preparing BVDV virus-like particles.

L'invention concerne des pseudo-particules virales du virus de la diarrhée virale des bovins (virus BVD), un ARN polycistronique et un ADN correspondant codant pour une polyprotéine de protéines structurales du virus BVD qui suffisent pour former les pseudo-particules virales du virus BVD, un vecteur viral codant pour des facteurs et des protéines structurales pour l'assemblage des pseudo-particules virales du virus BVD, un vaccin comprenant ces particules, une trousse de diagnostic et des procédés permettant de préparer ces pseudo-particules virales.

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