Bystander suppression of autoimmune diseases

Details Bystander suppression of autoimmune diseases Bystander suppression of autoimmune diseases

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 9/72 (2006.01) A61P 3/10 (2006.01) A61K 38/26 (2006.01)

Patent

CA 2117492

The invention is directed to a method for treating autoimmune diseases in mammals, the method comprising administering to the mammals an effective amount for treating the diseases of a bystander antigen, the antigen eliciting the release of transforming growth factor beta (TGF-.beta.) at a locus within the body of the mammals wherein T-cells contributing to autoimmune response are found to suppress the T-cells contributing to the disease. The invention is directed also to compositions comprising bystander antigens useful in the treatment of autoimmune diseases in mammals and to pharmaceutical formulations thereof.

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