C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/109, 260/233
C12P 17/06 (2006.01) C07D 493/20 (2006.01) C07H 19/01 (2006.01) C12P 17/18 (2006.01) C12P 19/62 (2006.01)
Patent
CA 1164820
ABSTRACT OF THE DISCLOSURE There are disclosed certain new compounds related to C-076 compounds which have been produced by a mutant of the culture that produced the original C-076 compounds and isolated from the fermentation broth thereof. The compounds retain the C-076 16- membered cyclic backbone, however, the groups attached thereto are considerably modified from the original C-076 compounds. The new compounds have been found to retain the biological activity of the parent C-076 compounds. The compounds are thus potent anti- parasitic agents and compositions and methods for such uses are also disclosed.
395869
Goegelman Robert T.
Gullo Vincent P.
Kaplan Louis
Goudreau Gage Dubuc
Merck & Co. Inc.
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