C-13 prostagland in analogs

Details C-13 prostagland in analogs C-13 prostagland in analogs

C - Chemistry, Metallurgy

07

D

260/356, 260/362

C07D 307/93 (2006.01) C07C 57/30 (2006.01) C07C 57/72 (2006.01) C07C 405/00 (2006.01) C07D 307/935 (2006.01) C07D 309/12 (2006.01) C07D 311/94 (2006.01) C07F 9/40 (2006.01) C12N 9/18 (2006.01)

Patent

CA 1064483

ABSTRACT OF THE DISCLOSURE This invention comprises certain analogs of the prosta- glandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmaco- logical purposes as the prostaglandins. Among these pur- poses are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

253511

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