C-2 modified erythromycin derivatives

Details C-2 modified erythromycin derivatives C-2 modified erythromycin derivatives

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2372270

A compound having the formula selected from the group consisting of a compound of formula (I), a compound of formula (II), and a compound of formula (III) as well as pharmaceutically acceptable salts, esters, solvates, metabolites, and prodrugs thereof, are useful in treating bacterial infections. Also provided are pharmaceutically acceptable compositions, methods of treating bacterial infections, and processes for the preparation of the compounds.

Cette invention concerne un composé dont la formule est prise dans le groupe comprenant un composé de formule (I), un composé de formule (II) et un composé de formule (III) ainsi que des sels, des esters, des solvants, des métabolites, et des promédicaments de ces composés acceptables au plan pharmaceutique, et qui convient pour le traitement des infections bactériennes. L'invention concerne également des compositions acceptables au plan pharmaceutique et des méthodes de traitement d'infections bactériennes ainsi que des procédés de préparation de ces composés.

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